Measurement of particle size in (biobased) nanomaterials

The existing and future generation of nanomaterials often consist of mixtures of wholly or partly biobased materials. Think of biomedical materials (nutraceutical and pharmacological applications) and polymer mixtures. Traditional particle characterization methods, such as DLS and LD, make it difficult to measure these mixtures correctly. These methods provide only average data over the whole sample, with all particles considered the same, just of different sizes. This can be a limitation in various R&D and QC tasks. The relatively new particle characterization method SPES (Single Particle Extinction and Scattering) solves that problem.

SPES-method particularly suitable for mixtures of particles

SPES is an optical particle characterization method, which is particularly suitable for heterogeneous suspensions; mixtures of particles and thus for (biobased) nanomaterials. But also biological heterogeneous liquids (serums, plasma, urine and cell lysate) are mixtures of particles. The main advantage over existing particle characterization methods is that the SPES method/Classizer ONE from EOS offers the possibility to measure mixtures of particles in liquids in high resolution, even when other particles are present. This produces “clouds” of particles that can be interpreted individually. This is subject to the condition that the particles are located in the range of 100 nm to 20 µm.

How does the SPES particle measurement work?

SPES retrieves the optical properties of the individual particles. It classifies the particle populations in a mixture based on this information. Thus, when interpreting the various particles, no additional information is required about the optical parameters, as is the case with other particle characterization methods.

Free webinar: Particle size characterization of (biobased) nanomaterials

You can get acquainted with the SPES method via this free webinar organized by Inventech. The presenter of this webinar is the inventor of the SPES technique, scientist Tiziano Sanvito (PhD), and is in the English language.

More information on the particle size characterization method SPES

For more information on particle characterization methods for (biobased) nanomaterials, please contact Marc Steinmetz via email or +31 (0)162 460404.

Contact Inventech today

Particle characterization method for existing and future (biobased) nanomaterials

SPES game changer for measuring mixtures of particles in liquids in high resolution